Name: Strengthening science, together. RIFM's 3rd Annual Science Symposium
Start: 06/11/2024 01:00 PM +00:00
End: 06/11/2024 05:00 PM +00:00

Scroll down to download the poster "Development of a curated dataset to facilitate the derivation of inhalation &nbsp;Threshold of Toxicological Concern (TTC)"

Inhalation TTC

Scroll down to download A Study to Evaluate the Kinetics, Metabolism and Toxicity of a Fragrance Material (Cinnamaldehyde) in an In Vitro Three-Organ Integrated Microphysiological System (MPS) Model

The MPS Model

Scroll down to download Analyzing the role of vinyl- and vinylene-containing fragrance ingredients in skin sensitization using the SENS-IS assay

The SENS-IS assay

Click here to download Detailed aggregate exposure analysis shows that exposure to fragrance ingredients in consumer products is low: Many orders of magnitude below thresholds of concern

Low Exposure Paper

Scroll down to download Prediction of points of departure for fragrance ingredients using integrated OECD in vitro models and assessment of weight of evidence potency categories

PoDs using OECD & WoE potency

Scroll down to download Determining a point of departure for skin sensitization potency and quantitative risk assessment of fragrance ingredients using the GARDskin dose-response assay

GARDskin

<a href="https://setac.onlinelibrary.wiley.com/doi/full/10.1002/etc.5865" target="_blank" rel="noopener">Click here to read A Chronic Aquatic Hazard Assessment for the Perfume Raw Material Octahydro-tetramethyl-naphthalenyl-ethanone (OTNE)</a>

OTNE

In our opening mainstage session, RIFM President Anne Marie Api, PhD, Fellow ATS, and Director of Scientific Operations Danielle Botelho, PhD, will lead us in a significant next-generation safety assessment milestone and provide an overview of RIFM's animal-free new approach methodology (NAMs) research strategy. RIFM Principal Scientist Gretchen Ritacco, MS, and Senior Scientist Isabelle Lee, PhD, will present on the strength of real-world exposure, with presentations on the Creme RIFM Aggregate Exposure Model and the findings of the collaborative Low Exposure Paper.

Anne Marie Api

Danielle Botelho

Gretchen Ritacco

Isabelle Lee

Gary Sullivan

The strength of what we know: RIFM s next-generation risk assessments and real-world exposure

Click on the Rooms tab in the upper menu bar, then choose The strength of real-world-exposure.

Olive Chon

The strength of real-world exposure

Click on the Rooms tab in the upper menu bar, then choose The strength of the RIFM Database.

Mary Mircovich

Meghan Barreto

Kimberly Arencibia

Christen Sachse-Vasquez

The strength of the RIFM Database

Click on the Rooms tab in the upper menu bar, then choose Below the threshold: Exposure-based waiving

Kaushal Joshi

Nikaeta Sadekar

Maura Lavelle

Aurelia Lapczynski

Below the threshold: Exposure-based waiving

Click on the Rooms tab in the upper menu bar, then choose Collaborative opportunities to advance the Creme RIFM Aggregate Exposure Model

Collaborative opportunities to advance the Creme RIFM Aggregate Exposure Model

In our second mainstage session, RIFM President Anne Marie Api, PhD, Fellow ATS, and Director of Scientific Operations Danielle Botelho, PhD, provide more details on the real-world impact of RIFM's animal-free new approach methodology (NAMs) research strategy. RIFM Senior Scientist Holger Moustakas, PhD, and Senior Associate Scientist Jake Muldoon, PhD, will present on the strength of chemical clustering, showing how it can be harnessed to successfully gain insights into fragrance materials with limited or no data.

Holger Moustakas

Jake Muldoon

Terry Schultz

The strength of chemical clustering and the legacy of read-across

Click on the Rooms tab in the upper menu bar, then choose The future of RIFM's animal-free read-across strategy

The future of RIFM's animal-free read-across strategy

Click on the Rooms tab in the upper menu bar, then choose Foundational datasets and powerful tox tools

Yax Thakkar

Arianna Bartlett

Foundational datasets and powerful tox tools

Click on the Rooms tab in the upper menu bar, then choose The Maximum Acceptable Concentration process and the role of Quantitative Risk Assessment 2

The Maximum Acceptable Concentration process and the role of Quantitative Risk Assessment 2

Click on the Rooms tab in the upper menu bar, then choose The strength of RIFM&rsquo;s chemical signatures: A read-across case study

Agenda

Speakers22 Speakers

Anne Marie Api

Danielle Botelho

Gretchen Ritacco

Isabelle Lee

Christen Sachse-Vasquez

Kimberly Arencibia

Kaushal Joshi

Nikaeta Sadekar

Maura Lavelle

Aurelia Lapczynski

Holger Moustakas

Jake Muldoon

Yax Thakkar

Arianna Bartlett

Mary Mircovich

Meghan Barreto

Terry Schultz

Dan Liebler

Olive Chon

Sean Farrell

Cesar Scrochi

Gary Sullivan

Studies7 Studies

Inhalation TTC

The MPS Model

The SENS-IS assay

Low Exposure Paper

PoDs using OECD & WoE potency

GARDskin

OTNE

Agenda

Speakers.css-2zwi6c{margin:0;font-size:1.4rem;font-weight:500;line-height:1.5;color:#494949;font-family:'Poppins',sans-serif;margin-left:0.8rem;}22 Speakers

Anne Marie Api

Danielle Botelho

Gretchen Ritacco

Isabelle Lee

Christen Sachse-Vasquez

Kimberly Arencibia

Kaushal Joshi

Nikaeta Sadekar

Maura Lavelle

Aurelia Lapczynski

Holger Moustakas

Jake Muldoon

Yax Thakkar

Arianna Bartlett

Mary Mircovich

Meghan Barreto

Terry Schultz

Dan Liebler

Olive Chon

Sean Farrell

Cesar Scrochi

Gary Sullivan

Studies.css-14sv5ey{margin:0;font-size:1.4rem;font-weight:500;line-height:1.5;color:#494949;font-family:'Poppins',sans-serif;color:#FFFFFF;margin-left:0.8rem;font-weight:400;}7 Studies

Inhalation TTC

The MPS Model

The SENS-IS assay

Low Exposure Paper

PoDs using OECD & WoE potency

GARDskin

OTNE

Speakers22 Speakers

Studies7 Studies